Table 1.

Criteria determining the therapeutic and social value of medicines (Szalay et al., 2011).

Criteria determining the therapeutic value of medicines	Criteria determining the social value of medicines
Relative effectiveness (i.e., QALY gain)	Severity of the disease
Safety	Impact on society if not treated (e.g., spread of infection)
Cost-effectiveness	Social value (e.g., orphan drugs)
Whether it is a first or second option or adjunctive treatment	Risk of abuse
Whether it is a causal, prophylactic or symptomatic treatment	Impact on total costs