Table S1.

Characteristics of studies included in the meta-analysis

First author	Year	miRNA	Ethnicity	Cancer type	Sample type	Method	Cancer grade	Case (H)	Control (L)
Liu	2012	miR-371-5p	Asian	Gastric cancer	Serum	qRT-PCR	I–IV	40	41
Yamashita	2012	miR-372	Asian	CRC	Tissue	qRT-PCR	\	72	72
Gu	2012	miR-372	Asian	HCC	Tissue	qRT-PCR	\	65	43
Li	2013	miR-372	Asian	Gliomas	Tissue	qRT-PCR	\	78	50
Eichelser	2013	miR-373	Caucasian	Breast cancer	Serum	qRT-PCR	M0	120	40
M1	32
Chen	2013	miR-373	Caucasian	Breast ductal carcinoma	Plasma	qRT-PCR	I–IV	35	25
Syring	2014	miR-371-3p	Caucasian	Testicular germ cell cancer	Serum	qRT-PCR	\	59	101
Tu	2015	miR-372	Asian	OSCC	Tissue	qRT-PCR	\	50	50
Tu	2015	miR-373	Asian	OSCC	Tissues	qRT-PCR	\	50	50
Meng	2015	miR-373	Caucasian	EOC	Serum	qRT-PCR	\	47	46
Wu	2015	miR-372	Asian	HCC	Tissue	ISH	\	33	87
Bellmunt	2016	miR-372	Caucasian	UC	Tissue	qRT-PCR	\	40	40
Dieckmann	2017	miR-371-3p	Caucasian	Germ cell tumours	Serum	qRT-PCR	CS1	107	106
CS2-CS3	43
Hua	2017	miR-373	Asian	Pancreatic cancer	Serum	qRT-PCR	I–IV	103	50
Zhang	2017	miR-373	Asian	BCa	Tissues	qRT-PCR	\	40	40
Hua	2017	miR-373	Asian	Pancreatic cancer	Serum	qRT-PCR	\	50	53
Jing	2017	miR-373	Asian	Gliomas	Tissues	qRT-PCR	\	83	87
Wang	2017	miR-373	Asian	NSCLC	Tissues	qRT-PCR	\	46	46

Note: M0, patients with primary breast cancer after surgery and before chemotherapy; M1, patients with distant metastases at diagnosis (We roughly incorporated M0 into the early stage, and correspondingly incorporate M1 into the late stage).

Abbreviations: qRT-PCR, quantitative real-time PCR; H, high expression; L, low expression; CS, clinical stage; UC, urothelial carcinoma; OSCC, oral squamous cell carcinoma; HCC, hepatocellular carcinoma; CRC, colorectal cancer; BCa, bladder cancer; NSCLC, non-small cell lung cancer; EOC, epithelial ovarian cancer.