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. 2019 May 26;10(11):2425–2433. doi: 10.7150/jca.31359

Figure 1.

Figure 1

The PI3/AKT/mTOR signaling pathway in tumor cells and regulation by bioactive peptides of the PI3/AKT/mTOR signaling pathway. The PI3/AKT/mTOR pathway is an important signaling pathway for intracellular glucose metabolism, lipid metabolism, and protein metabolism. Small regulatory polypeptide of amino acid response (SPAR) reduced the activity of mTORC, while tumstatin inhibited the mTOR pathway.