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. 2019 May 21;10(10):2176–2184. doi: 10.7150/jca.32731

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The clinical significance of UBE2C expression level in melanoma. (A) TCGA's datasets were used for bioinformatics analysis to determine UBE2C mRNA level in melanoma. A higher UBE2C mRNA expression level was found in melanoma than that in normal tissue (p<0.05). (B) According to the data from KM plotter, high UBE2C mRNA level was associated with poor overall survival of the patients with melanoma (p<0.01). HR, hazard ratio. (C) qRT-PCR assay validated UBE2C overexpression in melanoma using fresh tissues (p<0.01).