Table 2.
Uni- and multivariate Cox regression analyses evaluating variables associated with radiographic PFS
| Univariate | Multivariate | |||||
|---|---|---|---|---|---|---|
| HR | 95% CI | p | HR | 95% CI | p | |
| Age | 0.975 | 0.913-1.042 | 0.454 | |||
| BMI | 1.029 | 0.871-1.216 | 0.735 | |||
| Preoperative PSA | 0.990 | 0.971-1.009 | 0.283 | |||
| Operative type | ||||||
| Open | Reference | |||||
| Robotic | 0.737 | 0.243-2.240 | 0.591 | |||
| Pathologic T stage | ||||||
| ≤ pT2 | Reference | |||||
| ≥ pT3 | 2.244 | 0.277-18.161 | 0.449 | |||
| Pathologic GS | ||||||
| 7 | Reference | Reference | ||||
| ≥8 | 2.799 | 1.077-7.274 | 0.035 | 2.539 | 0.976-6.603 | 0.056 |
| Total number of removed LNs | 0.962 | 0.896-1.032 | 0.280 | |||
| Total number of positive LNs | 1.068 | 0.909-1.256 | 0.423 | |||
| LN density | 0.762 | 0.110-5.275 | 0.783 | |||
| ECE | 0.846 | 0.276-2.592 | 0.769 | |||
| SVI | 1.958 | 0.652-5.883 | 0.231 | |||
| PSM | 1.303 | 0.431-3.942 | 0.639 | |||
| LVI | 1.272 | 0.432-3.743 | 0.662 | |||
| Adjuvant therapy | 2.690 | 1.099-6.583 | 0.030 | 1.227 | 0.397-3.794 | 0.722 |
| BCR | 1.812 | 0.727-4.512 | 0.202 | |||
| PSA persistence | 3.527 | 1.278-9.737 | 0.015 | 2.927 | 1.021-8.393 | 0.046 |
BCR: biochemical recurrence, BMI: body mass index, ECE: extracapsular extension, GS: Gleason score, LN: lymph node, PFS: progression-free survival, PSM: positive surgical margin, SVI: seminal vesicle invasion