Table 1.
Association between the expression of PPARα and clinicopathological characteristics
| Total patients | PPARα expression | |||
|---|---|---|---|---|
| Variable | No(%) | Low group | High group | P |
| Race | 0.223 | |||
| Black or frican american | 52(10.2) | 29(55.8) | 23(44.2) | |
| White | 452(88.3) | 221(48.9) | 231(51.1) | |
| Asian | 8(1.5) | 6(75.0) | 2(25.0) | |
| Age, Mean ± SD, (years) | 60.6 ±12.1 | 60.6 ±12.4 | 60.4±11.9 | 0.746 |
| Age | 0.774 | |||
| <65 | 324(63.3) | 165(50.9) | 159(49.1) | |
| ≥65 | 188(36.7) | 99(52.7) | 89(47.3) | |
| Gender | 0.013 | |||
| Male | 332(64.8) | 185(55.7) | 147(44.3) | |
| Female | 180(35.2) | 79(43.9) | 101(56.1) | |
| Tumor dimension, Mean ± SD | 1.68 ±0.655 | 1.61 ±0.611 | 1.74 ±0.693 | 0.034 |
| Laterality | 0.600 | |||
| Left | 238(46.5) | 118(49.6) | 120(50.4) | |
| Right | 273(53.3) | 137(50.2) | 136(49.8) | |
| Bilateral | 1(0.2) | 1(100) | 0(0) | |
| Neoadjuvant therapy | 0.324 | |||
| No | 495(96.7) | 245(49.5) | 250(50.5) | |
| Yes | 17(3.3) | 11(64.7) | 6(35.3) | |
| Stage | <0.001 | |||
| Ⅰ | 259(50.7) | 114(43.2) | 145(56.8) | |
| Ⅱ | 52(11.0) | 26(44.1) | 26(55.9) | |
| Ⅲ | 119(23.0) | 68(56.1) | 51(43.9) | |
| Ⅳ | 82(15.3) | 56(68.3) | 26(31.7) | |
| Grade | <0.001 | |||
| 1 | 14(2.64) | 4(28.6) | 10(71.4) | |
| 2 | 220(44.3) | 101(43.8) | 119(56.2) | |
| 3 | 204(38.9) | 102(49.5) | 102(50.5) | |
| 4 | 74(14.2) | 57(76.0) | 17(24.0) |