Figure 5.

Disruption of TRPA1 decreases infiltration of leukocytes, T cells and mast cells in IMQ‐induced PsD. Representative images of immunohistochemical staining (scale bar = 50 μm) and quantification of (A) CD 45 + leukocytes, (B) F4/80 + macrophages, (C) CD3 + T cells and (D) mast cells. n = 6 per group. All skin lesions were collected after vehicle/IMQ treatment for 5 days. One‐way ANOVA followed by post‐hoc comparison (Tukey's HSD) test was analysed. Mean ± SEM values are indicated (****P < 0.0001). IMQ, imiquimod; TRPA1, Transient receptor potential ankyrin 1