Figure 1.

Overview of multi-level data domains and information collection in the ZOE 2.0 study, including the person and family level (inner circle) and the community level (middle and outer circles). Boxes with solid outline represent currently collected data, dash outline patterns represent bio-banked (not currently analyzed) biological samples (e.g., supragingival microbiome) and dotted outline patterns represent envisaged future additions to the protocol (e.g., administrative data/insurance claims and intra-oral imaging).