Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Jun 20;9:4643. doi: 10.1038/s41598-019-39317-9

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Radiation-induced increase in extracellular ATP and the effect of TAT-Gap19 after single and fractionated irradiation. ATP release was measured 1 h, 6 h and 72 h after single radiation exposure (0.1 and 5 Gy) in (a) TICAE cells and (b) TIME cells and 72 h after fractionated irradiation exposure in (c) TICAE cells and (d) TIME cells. TAT-Gap19 was used to block Cx43 hemichannels. Data were analyzed with a nonparametric Mann-Whitney T-test. Values represent average ± SEM of 6–8 biological replicates. *Indicates the statistical differences compared to the respective 0 Gy controls, and statistical difference between single and fractionated irradiation for the same radiation doses. ^•Indicates the statistical difference compared to the respective control condition (not treated with TAT-Gap 19), (c,d) ^•indicates the statistical differences for either single or fractionated irradiation compared to their respective 0 Gy controls; ^*/•p < 0.05; ^**/••p < 0.01; ^{***/•••}p < 0.0001.