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. 2019 Jun 19;2:216. doi: 10.1038/s42003-019-0475-6

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Giant virus infectivity profiles and signatures in A. castellanii Neff analyzed by high-content screening. Targeted algorithms for image analysis were configured on the negative control A. castellanii Neff stained with SYBR Green. The mean values are represented for each parameter (n = 3 independent experiments). Error bars represent standard deviations. In addition, p-values were generated for each parameter. a Cell Shape P2A Index (p-value of 0.02). b SYBR Green Average Intensity p-value of 0.008 and c total cell count (p-value of 0.005)