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. 2019 Jun 19;9:8771. doi: 10.1038/s41598-019-43998-7

Table 1.

DE miRNAs in Group 4 vs Group 1 comparison predicted to target genes in the AR and PPAR signaling pathways.

MiRNA ID Expr p-value MIRNA Expr Fold Change Symbol MRNA Expr log Fold Change Pathway
hsa-miR-98-5p 0.00000126 −2.271 PPARGC1B 2.893 LPS/IL-1 Mediated Inhibition of RXR Function
hsa-miR-301b-3p 0.0000118 −6.39 PPARG 6.658 Adipogenesis pathway, ERK/MAPK Signaling, FXR/RXR Activation,
hsa-miR-138-5p 0.00781 −5.901 PPARGC1A 8.296 AMPK Signaling, Estrogen Receptor Signaling, FXR/RXR Activation
hsa-miR-27b-3p 6.84E-07 −2.189 PPARG 6.658 Adipogenesis pathway, ERK/MAPK Signaling, FXR/RXR Activation,
hsa-miR-92a-1-5p 0.00329 −5.08 PPARGC1A 8.296 AMPK Signaling, Estrogen Receptor Signaling, FXR/RXR Activation
hsa-miR-92a-1-5p 0.00329 −5.08 PPARGC1B 2.893 LPS/IL-1 Mediated Inhibition of RXR Function
hsa-let-7d-3p 0.00313 −2.569 PRKACB 2.166 AMPK Signaling, Amyloid Processing, Androgen Signaling
hsa-miR-128-3p 0.00111 −2.576 PRKD1 2.769 14-3-3-mediated Signaling, Aldosterone Signaling in Epithelial Cells, Androgen Signaling
hsa-miR-138-5p 0.00781 −5.901 GNG2 2.87 Androgen Signaling, Antiproliferative Role of Somatostatin Receptor 2
hsa-miR-148b-3p 0.00000885 −2.159 MRAS 2.83 14-3-3-mediated Signaling, Actin Cytoskeleton Signaling
hsa-miR-182-5p 0.0000627 −2.718 PRKACB 2.166 AMPK Signaling, Amyloid Processing, Androgen Signaling, Axonal Guidance Signaling
hsa-miR-3656 0.00000101 5.481 POLR2L −1.226 Androgen Signaling, Assembly of RNA Polymerase II Complex, CREB Signaling in Neurons
hsa-miR-539-3p 0.00902 2.178 GNA14 −2.398 Androgen Signaling, Axonal Guidance Signaling
hsa-miR-487b-3p 0.00000964 2.389 SRY −1.544 Androgen Signaling, Neuroprotective Role of THOP1 in Alzheimer’s Disease
hsa-miR-615-3p 0.00922 −5.078 AR 5.175 Androgen Signaling
hsa-miR-7977 0.00418 −2.261 GNG2 2.87 Androgen Signaling, Antiproliferative Role of Somatostatin Receptor 2, Axonal Guidance Signaling