Table 2.
Hematology profile in non-tumor bearing athymic nude mice administered with normal saline. Two mice per group were used. Standard ranges were obtained in house from 100 normal BALB/c mice of 8–12 weeks age
| Hematological parameters | Control | 10 mg/kg | 20 mg/kg | Standard |
|---|---|---|---|---|
| White blood cells (×103 μl) | 4.71/4.42 | 4.90/4.95 | 5.87/5.74 | 4.5–9.1 |
| Red blood cells (×106/μl) | 9.76/10.70 | 10.51/9.84 | 10.25/9.30 | 7.51–16.1 |
| Hemoglobin (g/dL) | 14.5/13.0 | 15.2/14.2 | 14.9/13.9 | 12.8–16.1 |
| Hematocrit (%) | 44.8/41.8 | 47.9/45.3 | 46.9/44.7 | 34–50 |
| Lymphocytes (%) | 67.2/78.8 | 50.4/61.4 | 55.4/63.1 | 49–82 |
| Monocytes (%) | 2.64/4.24 | 4.54/5.24 | 3.14/4.64 | 2–8 |
| Eosinophils (%) | 0.24/0.34 | 0.04/0.74 | 0.54/0.64 | 0–3 |
| Basophils (%) | 0.24/0.74 | 0.34/0.34 | 0.54/0.24 | 0–3 |
| Platelet (×103 μl) | 507/410 | 560/483 | 526/744 | 115–1037 |
| Mean corpuscular volume (fL) | 45.9/45.8 | 45.6/46.0 | 45.8/48.1 | 41–60 |
| Mean corpuscular hemoglobin (pg) | 14.9/14.3 | 14.5/14.4 | 14.5/14.9 | 13–19 |