Fig. 6. Summary and ratios of colocalization.

(A) A stochastic aggregation of the labeled/unlabeled peptides should bring to the formation of uniformly labeled fibrils. Our experiments indicate a different scenario where only a fraction of the fibrils has a labeled component. Other fibrils, dark in the STED analysis, are unlabeled. These two products are the results of different aggregation pathways. (B) Table showing the ratio of colocalization calculated for the different peptide species and dye-to-protein ratios.