Table 1. Macular Sensitivity in Stargardt Disease and Its Association With Demographic Features.
| Outcome, Independent Variable | Eyes With Good and Fair Pattern Placement | |||
|---|---|---|---|---|
| Univariate | Multivariate | |||
| β Estimate (95% CI) | P Value | β Estimate (95% CI) | P Value | |
| Mean sensitivity, dBa | ||||
| Current age per y | −0.086 (−0.13 to −0.041) | <.001 | −0.04 (−0.09 to 0.02) | .20 |
| Current age ≥50 y | −3.13 (−4.78 to −1.47) | <.001 | NA | NA |
| Age at onset >18 y | 0.01 (−1.44 to 1.47) | .98 | NA | NA |
| Duration of Stargardt disease, y | −0.21 (−0.28 to −0.14) | <.001 | −0.18 (−0.27 to −0.09) | <.001 |
| Male sex | 0.55 (−0.86 to 1.96) | .44 | NA | NA |
| Nonwhite race/ethnicity | 0.26 (−1.75 to 2.27) | .80 | NA | NA |
| Count of normal points | ||||
| Current age per y | −0.34 (−0.54 to −0.15) | <.001 | −0.14 (−0.39 to 0.10) | .25 |
| Current age ≥50 y | −13.48 (−20.71 to −6.26) | <.001 | NA | NA |
| Age of onset >18 y | 0.77 (−5.29 to 6.82) | .80 | NA | NA |
| Duration of Stargardt disease, y | −0.83 (−1.13 to −0.52) | <.001 | −0.71 (−1.10 to −0.32) | <.001 |
| Male sex | 0.65 (−5.23 to 6.54) | .83 | NA | NA |
| Nonwhite race/ethnicity | 2.05 (−6.11 to 10.21) | .63 | NA | NA |
| Count of deep scotoma points | ||||
| Current age per y | 0.29 (0.13 to 0.45) | <.001 | 0.09 (−0.09 to 0.27) | .32 |
| Current age ≥50 y | 9.25 (2.98 to 15.52) | .004 | NA | NA |
| Age of onset >18 y | −0.13 (−5.08 to 4.81) | .96 | NA | NA |
| Duration of Stargardt disease, y | 0.78 (0.50 to 1.05) | <.001 | 0.70 (0.37 to 1.04) | <.001 |
| Male sex | −1.37 (−6.13 to 3.40) | .57 | NA | NA |
| Nonwhite race/ethnicity | 1.1 (−5.67 to 7.86) | .75 | NA | NA |
Abbreviation: NA, not applicable.
a
n = 323 eyes.