Table 1.
Genes present in the MetaGx gene signature.
| Gene Symbol | Description | Entrez ID | Direction | |
|---|---|---|---|---|
| 1 | ACKR3 | atypical chemokine receptor 3 | 57007 | 1 |
| 2 | ACTN4 | actinin alpha 4 | 81 | 1 |
| 3 | ARHGAP21 | Rho GTPase activating protein 21 | 57584 | 1 |
| 4 | C12orf49 | chromosome 12 open reading frame 49 | 79794 | 1 |
| 5 | CACNB3 | calcium voltage-gated channel auxiliary subunit beta 3 | 784 | 1 |
| 6 | CAMK1D | calcium/calmodulin dependent protein kinase ID | 57118 | 1 |
| 7 | CAMSAP3 | calmodulin regulated spectrin associated protein family member 3 | 57662 | −1 |
| 8 | CBFB | core-binding factor beta subunit | 865 | 1 |
| 9 | CDC37L1 | cell division cycle 37 like 1 | 55664 | −1 |
| 10 | CDK19 | cyclin dependent kinase 19 | 23097 | 1 |
| 11 | CLDN4 | claudin 4 | 1364 | 1 |
| 12 | CMBL | carboxymethylenebutenolidase homolog | 134147 | 1 |
| 13 | COP1 | COP1, E3 ubiquitin ligase | 64326 | 1 |
| 14 | CRABP2 | cellular retinoic acid binding protein 2 | 1382 | 1 |
| 15 | CSE1L | chromosome segregation 1 like | 1434 | 1 |
| 16 | DARS2 | aspartyl-tRNA synthetase 2, mitochondrial | 55157 | 1 |
| 17 | DDB2 | damage specific DNA binding protein 2 | 1643 | −1 |
| 18 | DPP4 | dipeptidyl peptidase 4 | 1803 | 1 |
| 19 | EGFR | epidermal growth factor receptor | 1956 | 1 |
| 20 | FAM189A2 | family with sequence similarity 189 member A2 | 9413 | −1 |
| 21 | GSTZ1 | glutathione S-transferase zeta 1 | 2954 | −1 |
| 22 | IMPDH1 | inosine monophosphate dehydrogenase 1 | 3614 | 1 |
| 23 | IRF3 | interferon regulatory factor 3 | 3661 | 1 |
| 24 | KATNAL1 | katanin catalytic subunit A1 like 1 | 84056 | 1 |
| 25 | KIF11 | kinesin family member 11 | 3832 | 1 |
| 26 | LATS2 | large tumor suppressor kinase 2 | 26524 | 1 |
| 27 | LOXL2 | lysyl oxidase like 2 | 4017 | 1 |
| 28 | MOCS1 | molybdenum cofactor synthesis 1 | 4337 | −1 |
| 29 | MREG | melanoregulin | 55686 | −1 |
| 30 | MSC | musculin | 9242 | 1 |
| 31 | MYADM | myeloid associated differentiation marker | 91663 | 1 |
| 32 | MYLK3 | myosin light chain kinase 3 | 91807 | −1 |
| 33 | NAE1 | NEDD8 activating enzyme E1 subunit 1 | 8883 | 1 |
| 34 | NID2 | nidogen 2 | 22795 | 1 |
| 35 | OPRM1 | opioid receptor mu 1 | 4988 | 1 |
| 36 | PLAU | plasminogen activator, urokinase | 5328 | 1 |
| 37 | PPEF1 | protein phosphatase with EF-hand domain 1 | 5475 | 1 |
| 38 | PWP1 | PWP1 homolog, endonuclein | 11137 | 1 |
| 39 | RALY | RALY heterogeneous nuclear ribonucleoprotein | 22913 | 1 |
| 40 | RARRES3 | retinoic acid receptor responder 3 | 5920 | −1 |
| 41 | REX1BD | required for excision 1-B domain containing | 55049 | 1 |
| 42 | SERPINB2 | serpin family B member 2 | 5055 | 1 |
| 43 | SIPA1L2 | signal induced proliferation associated 1 like 2 | 57568 | 1 |
| 44 | STK3 | serine/threonine kinase 3 | 6788 | 1 |
| 45 | TERF2 | telomeric repeat binding factor 2 | 7014 | 1 |
| 46 | TEX261 | testis expressed 261 | 113419 | 1 |
| 47 | TGFBI | transforming growth factor beta induced | 7045 | 1 |
| 48 | TNFRSF18 | TNF receptor superfamily member 18 | 8784 | −1 |
| 49 | TPD52L2 | tumor protein D52 like 2 | 7165 | 1 |
| 50 | UTP6 | UTP6, small subunit processome component | 55813 | 1 |
| 51 | ZFAND2A | zinc finger AN1-type containing 2 A | 90637 | 1 |
| 52 | ZNF204P | zinc finger protein 204, pseudogene | 7754 | −1 |
| 53 | ZSCAN32 | zinc finger and SCAN domain containing 32 | 54925 | −1 |