. 2019 Jun 19;9:8770. doi: 10.1038/s41598-019-45165-4

Table 2.

Prognostic value of Pancreatic Cancer Gene Signatures.

	Gene Signature - Subtype	D Index	D Index 95% CI	D Index P	Log Rank Test P
1	MetaGx - All Patients	1.64	(1.37, 1.90)	1.9e-04	2.3e-06
2	MetaGx - basal	1.75	(1.31, 2.19)	1.1e-02	1.1e-03
3	MetaGx - classical	1.43	(1.09, 1.77)	3.7e-02	1.3e-02
4	Newhook PLos one^a - All Patients	1.22	(0.97, 1.47)	1.1e-01	1.2e-01
5	Newhook PLos one^a - basal	1.01	(0.80, 1.23)	9e-01	7.9e-01
6	Newhook PLos one^a - classical	0.99	(0.77, 1.20)	9e-01	6.2e-01
7	Haider Gen Med^b - All Patients	1.56	(1.23, 1.88)	6.8e-03	4.7e-06
8	Haider Gen Med^b- basal	1.22	(0.88, 1.57)	2.4e-01	2.2e-01
9	Haider Gen Med^b - classical	1.43	(1.15, 1.71)	1e-02	9.5e-02
10	Grutzmann Oncogene^c - All Patients	1.35	(1.22, 1.49)	1.3e-05	2.1e-06
11	Grutzmann Oncogene^c - basal	1.29	(0.91, 1.67)	1.7e-01	7.8e-03
12	Grutzmann Oncogene^c - classical	1.23	(1.01, 1.46)	6.2e-02	1.1e-01
13	Stratford PLos med^d - All Patients	1.39	(1.09, 1.68)	2.9e-02	6.3e-03
14	Stratford PLos med^d - basal	1.22	(1.01, 1.43)	6.4e-02	2.6e-01
15	Stratford PLos med^d- classical	1.29	(0.94, 1.63)	1.4e-01	6.7e-02

^aT. E. Newhook et al., A thirteen-gene expression signature predicts survival of patients with pancreatic cancer and identifies new genes of interest, PLoS One, vol. 9, no. 9, p. e105631, Sep. 2014.

^bS. Haider et al., A multi-gene signature predicts outcome in patients with pancreatic ductal adenocarcinoma, Genome Med., vol. 6, no. 12, p. 105, Dec. 2014.

^cR. Grutzmann et al., Meta-analysis of microarray data on pancreatic cancer defines a set of commonly dysregulated genes, Oncogene, vol. 24, no. 32, pp. 5079–5088, Jul. 2005.

^dJ. K. Stratford et al., A six-gene signature predicts survival of patients with localized pancreatic ductal adenocarcinoma, PLoS Med., vol. 7, no. 7, p. e1000307, Jul. 2010.