Table 3.
Univariate analysis of baseline factors associated with HT.
| Variables | Patients without HT (n = 502) | Patients with HT (n = 66) | p |
|---|---|---|---|
| Demographics | |||
| Age (year) | 61.9 ± 12.0 | 64.8 ± 10.9 | 0.062 |
| Sex (male) | 370 (73.7%) | 48 (72.7%) | 0.865 |
| Vascular risk factors | |||
| Cigarette smoking | 290 (57.8%) | 37 (56.1%) | 0.792 |
| Alcohol consumption | 202 (40.2%) | 27 (40.9%) | 0.917 |
| Atrial fibrillation | 73 (14.5%) | 27 (40.9%) | 0.001 |
| Coronary heart disease | 75 (14.9%) | 13 (19.7%) | 0.315 |
| Hypertension | 302 (60.2%) | 36 (54.5%) | 0.382 |
| Diabetes mellitus | 161 (32.1%) | 20 (30.3%) | 0.772 |
| Dyslipidemia | 314 (62.5%) | 39 (59.1%) | 0.586 |
| Previous stroke | 106 (21.1%) | 17 (25.8%) | 0.389 |
| Previous history of drugs | |||
| Antihypertensive drugs | 154 (30.7%) | 21 (31.8%) | 0.850 |
| Hypoglycemic agents/insulin | 70 (13.9%) | 6 (9.1%) | 0.276 |
| Statins | 5 (1.0%) | 0 (0.0%) | 1.000 |
| Anti-thrombotic agents | 56 (11.2%) | 11 (16.7%) | 0.192 |
| Baseline parameters | |||
| NIHSS score | 8 (4–12) | 12.5 (8–16) | 0.001 |
| SBP (mmHg) | 157.7 ± 26.7 | 159.2 ± 25.2 | 0.660 |
| DBP (mmHg) | 90 (80–100) | 91.5 (80–99) | 0.764 |
| Blood glucose (mmol/L) | 7.01 (6.05–8.73) | 7.24 (6.35–8.64) | 0.398 |
| Hhcy | 401 (79.9%) | 54 (81.8%) | 0.711 |
| Treatment | |||
| Time to treat (hour) | 3.0 (2.3–3.8) | 2.8 (2.2–3.6) | 0.444 |
| Low-dose thrombolysis | 142 (28.3%) | 15 (22.7%) | 0.342 |
| Bridging therapy | 35 (7.0%) | 19 (28.8%) | 0.001 |
HT, hemorrhagic transformation; NIHSS, National Institute of Health Stroke Scale; SBP, systolic blood pressure; DBP, diastolic blood pressure; Hhcy, hyperhomocysteinemia.