Table 2.

Genotypes in the 23 patients with AEDs-induced cross-reactivity.

Number	HLA-A	HLA-B	HLA-C	HLA-DRB1	Culprit drug
CR1	02:01/33:03	13:01/38:02	03:04/07:02	08:03/09:01	CBZ/LTG
CR2	02:03/11:01	13:01/13:01	03:04/03:04	12:02/16:02	CBZ/LTG
CR3	11:01/11:01	15:02/15:18	02:02/08:01	04:04/15:01	CBZ/OXC
CR4	11:01/31:01	15:01/56:04	01:02/03:03	14:54/15:02	CBZ/OXC
CR5	11:01/11:01	13:01/35:01	03:03/03:04	09:01/15:01	CBZ/OXC
CR6	02:07/02:07	46:01/46:01	01:02/01:02	09:01/09:01	CBZ/OXC
CR7	02:01/11:01	15:25/39:01	04:03/07:02	09:01/16:02	CBZ/OXC
CR8	11:01/11:02	13:01/58:01	03:02/03:04	03:01/15:01	CBZ/TPM
CR9	11:01/24:02	40:01/40:01	03:04/07:02	08:03/14:54	LTG/CBZ
CR10	24:02/24:02	39:01/48:01	07:02/15:02	12:02/15:01	LTG/CBZ
CR11	11:01/02:07	15:02/46:01	01:02/08:01	09:01/09:01	LTG/CBZ
CR12	11:01/74:02	13:01/51:01	08:01/14:02	03:01/14:04	LTG/CBZ
CR13	11:01/11:01	40:01/40:01	None	None	LTG/CBZ
CR14	02:01/33:03	40:01/58:01	03:02/15:02	03:01/11:01	LTG/OXC
CR15	02:03/11:01	40:01/40:01	04:03/07:66	12:02/15:01	LTG/OXC
CR16	02:03/11:02	40:01/40:01	07:02/07:02	15:01/15:02	LTG/LEV
CR17	02:03/24:02	35:01/40:01	03:04/04:01	09:01/14:05	LTG/VPA
CR18	30:01/30:01	13:02/13:02	06:02/06:02	07:01/07:01	LTG/TPM
CR19	02:03/02:07	46:01/38:02	01:02/07:02	04:05/16:02	PTH/LTG
CR20	02:07/23:01	45:01/46:01	01:02/06:02	07:01/08:03	PHT/OXC
CR21	02:07/02:07	13:01/46:01	01:02/03:04	07:01/15:01	OXC/LTG
CR22	11:01/11:01	13:01/15:25	03:04/04:03	12:02/12:02	VPA/LTG
CR23	02:01/24:20	13:01/40:01	03:02/07:02	12:02/15:01	PB/CBZ

AEDs, antiepileptic drugs.

Bold black indicates those alleles are significant.

None: individual was not subjected to HLA genotyping because of insufficient DNA.

^* Individual was positive for HLA-B^*13:01 and HLA-A^*11:02, or positive for HLA-B^*13:01 and HLA-C^*04:03.