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. 2019 Jun 11;10:612. doi: 10.3389/fneur.2019.00612

Table 1.

Maternal characteristics and perinatal outcomes by IQ.

IQ at 4 years IQ at 7 years
Characteristics IQ ≥90 IQ <70 χ2 P IQ ≥90 IQ <70 χ2 P
N(%) 18,656 (95.4) 904 (4.6) 20,447 (96.3) 784 (3.7)
Maternal age (year) 90.1 <0.0001 28.5 <0.0001
   <20 3,645 (19.5) 290 (32.1) 4,076 (19.9) 212 (27.0)
   20–24 6,634 (35.6) 295 (32.6) 7,528 (36.8) 242 (30.9)
   25–29 4,266 (22.9) 146 (16.2) 4,569 (22.4) 159 (20.3)
   30–34 2,462 (13.2) 103 (11.4) 2,555 (12.5) 107 (13.7)
   ≥ 35 1,649 (8.8) 70 (7.7) 1,719 (8.4) 64 (8.2)
Race 499.9 <0.0001 629.7 <0.0001
   White 10,763 (57.6) 180 (19.9) 12,527 (61.3) 134 (17.1)
   Black 7,305 (39.2) 666 (73.7) 7,253 (35.5) 617 (78.7)
   Other 588 (3.2) 58 (6.4) 667 (3.3) 33 (4.2)
Parity 32.7 <0.0001 64.2 <0.0001
   0 5,260 (28.3) 311 (34.6) 6,200 (30.4) 185 (23.7)
   1 4,412 (23.7) 146 (16.2) 4,908 (24.1) 127 (16.3)
   ≥ 2 8,944 (48.0) 443 (49.2) 9,296 (45.6) 468 (60.0)
Social economic status 584.7 <0.0001 746.0 <0.0001
   1 (Lowest) 923 (5.0) 160 (18.4) 926 (4.6) 150 (19.9)
   2 4,555 (24.8) 382 (43.7) 4,623 (23.0) 363 (48.1)
   3 5,832 (31.8) 256 (29.4) 6,254 (31.1) 188 (24.9)
   4 4,505 (24.5) 60 (6.9) 5,161 (25.7) 45 (6.0)
   5 (Highest) 2,552 (13.9) 14 (1.6) 3,146 (15.6) 8 (1.1)
Maternal education levels (year) 350.7 <0.0001 500.3 <0.0001
   Less than high school (≤9) 4,229 (22.7) 436 (48.2) 4,409 (21.6) 424 (54.1)
   High school (10–12) 11,748 (62.9) 446 (49.6) 12,655 (61.9) 352 (44.9)
   College and above (> 12) 2,679 (14.4) 22 (2.4) 3,383 (16.6) 8 (1.0)
   Married 15,198 (81.5) 598 (66.2) 130.1 <0.0001 16,877 (82.5) 504 (64.3) 169.5 <0.0001
Smoking during pregnancy 8,958 (48.3) 380 (42.4) 11.9 0.001 9,735 (47.9) 329 (42.4) 9.0 0.003
Maternal BMI (kg/m2) 3.7 0.295 27.8 <0.0001
   <18.5 2,594 (14.1) 107 (12.2) 3,071 (15.2) 89 (11.9)
   18.5–25 11,863 (64.4) 561 (64.2) 13,038 (64.6) 455 (60.8)
   25–30 2,637 (14.3) 139 (15.9) 2,728 (13.5) 126 (16.8)
   ≥ 30 1,331 (7.2) 67 (7.7) 1,343 (6.7) 78 (10.4)
Preterm delivary 76.5 <0.0001 153.2 <0.0001
   Early preterm 458 (2.4) 54 (6.0) 18,192 (89) 598 (76.3)
   Late preterm 1,617 (8.7) 127 (14.0) 1,754 (8.6) 120 (15.3)
   Term 16,581 (88.9) 723 (80.0) 501 (2.5) 66 (8.4)
Preeclampsia 425 (2.3) 32 (3.6) 6.1 0.014 463 (2.3) 30 (3.9) 8.2 0.004
Chronic hypertension 3,727 (20.0) 179 (19.9) 0.0 0.931 4,083 (20.0) 172 (22.1) 1.9 0.166
Gestational diabetes 438 (2.4) 11 (1.2) 4.9 0.027 483 (2.4) 11 (1.4) 3.0 0.081
Preexisting diabetes 290 (1.6) 9 (1.0) 1.8 0.181 324 (1.6) 7 (0.9) 2.3 0.126

IQ, intelligence quotient; Early preterm, Gestational age at birth <34 weeks;

Late preterm, Gestational age at birth ≥34 and <37 weeks;

Term, Gestational age at birth ≥37 and ≤ 44 weeks.