Table 2.

Diagnostic criteria for MEN1^* (8).

1. Occurrence of two or more primary MEN1-associated endocrine tumors (i.e., parathyroid adenoma, enteropancreatic tumor, and pituitary adenoma) 2. Occurrence of one of the MEN1-associated tumors in a first-degree relative of a patient with a clinical diagnosis of MEN 3. Identification of a germline MEN1 mutation in an individual who may be asymptomatic and has not yet developed serum biochemical or radiological abnormities indicative of tumor development

MEN1, multiple endocrine neoplasia type 1.

^*To make a diagnosis of MEN1, a patient must fulfill at least one of three criteria.