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. 2019 Jun 13;7:397. doi: 10.3389/fchem.2019.00397

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Copyright © 2019 Nichols and Machan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Proposed mechanism for CO oxidation by Ni,Fe CODH (Jeoung and Dobbek, 2007). (B) Active site of FADH in Escherichia coli with bound formate substrate (Boyington et al., 1997).