Percentage
(±SD, n = 3) of BAC recovered
from exposure medium after 48 h of exposure to RTgill-W1 in 96-well
plates. Panels (a)–(c), respectively, depict the percentages
recovered from L15/ex, L15/ex with 4 g/L BSA, and L15/ex with 10%
FBS. The recovered percentages are sorted by the concentration at
the start of the exposure (from low (C1) to high(C9), white to black
bars). The concentrations are 0.01–25 μM in L15/ex for
BAC10-BAC18, 0.04–50 μM for BAC10-BAC18 in L15/ex with
medium constituents, 0.2–250 μM for BAC8, and 0.5–500
μM for BAC6 in L15/ex or 0.5–1000 μM for BAC8 and
1.5–1000 μM for BAC6 in L15/ex with medium constituents.
The percentage of chemical not recovered from medium after exposure
is assumed to have sorbed to plastic and cells. Note that the red
stripes below the bars refer to recoveries calculated using estimated
concentrations after exposure. Actual concentrations could not be
established because they were below the limit of quantification. Estimations
were based on dilution factors.