Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Jun 2;10(12):2706–2719. doi: 10.7150/jca.31845

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Ivyspring International Publisher

This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY-NC) license (https://creativecommons.org/licenses/by-nc/4.0/). See http://ivyspring.com/terms for full terms and conditions.

PMC Copyright notice

CBX2 is highly expressed in HCC cell lines, and knockdown of CBX2 decreases the proliferation of human HCC cells in vitro. (A) High CBX2 expression was detected in HCC cells, including Hep3B, Bel-7402, Bel-5Fu, 97-H, SK-Hep-1 and Huh7 cells. Protein levels were monitored by western blot. (B) The intensities of western blots were quantified using Image Lab 5.0 software and were normalized to GAPDH. (C) Two of the CBX2 siRNAs (Si2 and Si3) significantly reduced the expression of CBX2 protein in both Huh7 and Bel-7402 cells. (D, E) CCK-8 assay demonstrated that knockdown of CBX2 by CBX2 siRNAs (Si2 and Si3) significantly decreased the proliferation of Huh7 and Bel-7402 cells.(* P < 0.05, ** P < 0.01).