Table 1.
The dysregulated miR-27a and its targets in various cancers.
| Diseases | Targeted gene | References |
|---|---|---|
| NSCLC | MET, EGFR | Acunzo et al (31) |
| hepatocellular carcinoma (HCC) | FOXO1 | Sun et al(34) |
| PPARγ | Li et al(35) | |
| prostate cancer(PCa) | PHB | Claire E. Fletcher et al(38) |
| RUNX-1 | Deng et al(13) | |
| COUP-TFII | Lin et al(42) | |
| renal cell carcinoma | EGFR | Li et al(16) |
| esophageal squamous cell carcinoma | FBXW7 | Wu et al(40) |
| colon cancer | SGPP1,Smad2 | Bao et al(25) |
| Calreticulin | TColangelo et al(19) | |
| cervical cancer | B4GALT3 | Sun et al(23) |
| oral squamous cell carcinoma | YAP1 | Zeng et al(41) |
| MCPH1 | Thejaswini Venkatesh et al(33) | |
| breast cancer | SPRY2 | Li et al(20) |
| TMEM170B | Li et al(18) | |
| BAK | Zhou et al(70) | |
| gastric cancer | P21 | Zhao et al(26) |
| ovarian tumor | ZBTB10 | Lai et al(58) |
| tumors or ischemic diseases | SEMA6A | Carmen Urbich et al(44) |
| osteosarcoma | CBFA2T3 | Zaidoun Salah1 et al(43) |
| bronchial cancer | Fbxw7 | Wang et al(22) |
| Glioblastoma (GBM) | MXI1 | Xu et al(29) |
| esophageal squamous cell carcinoma | KRAS | Jiang et al(17) |
| hepatocellular carcinoma (HCC) | P21 | Sun et al(34) |
| VE-cadherin | Jennifer A. Young et al(55) | |
| bladder urothelial carcinoma | SLC7A11 | Ross M Drayton et al(72) |