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. Author manuscript; available in PMC: 2019 Jun 20.
Published in final edited form as: Addict Biol. 2017 Oct 30;23(5):1145–1159. doi: 10.1111/adb.12569

Figure 1.

Figure 1

Genome-wide association study (GWAS) for problematic alcohol use and behavior in the GTP discovery sample. (a) Manhattan plot of the GWAS for total alcohol use disorders identification test score (N = 1036, rsl433375 P = 7.76 × 10–8, black line is Bonferroni-adjusted threshold for genome-wide significance). (b) Regional plot of single-nucleotide polymorphism (SNP) associations within 500 kb of rsl433375 (purple triangle) on chromosome 4. Several SNPs are ir linkage disequilibrium with the top SNP