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. Author manuscript; available in PMC: 2019 Jun 20.
Published in final edited form as: Int J Pharm. 2019 Apr 16;564:281–292. doi: 10.1016/j.ijpharm.2019.04.022

Figure 12. Cul5 AuNPs sensitize resistant Cul5 KD cells to 17-AAG.

Figure 12.

A. WT AU565 cells were treated with increasing amounts of free 17-AAG or increasing amounts of free 17-AAG plus 10 μg of system 2. After 48 hours incubation cell cytotoxicity was evaluated via MTT assay. * p = 0.0206 B. Cul5 KD cells were incubated with increasing concentration of free 17-AAG or free 17-AAG plus 10 μg system 2. After 48 hours cell viability was assessed via MTT assay. **** p < 0.0001, *** p = 0.007.