Figure 10. Transmission electron microscopy (TEM) images of nuclei of Vero cells at 20 hpi with R7041(∆Us3).
( A) RCs (replication centres) contain hundreds of B-capsids (with scaffold) and C-capsids (with DNA) as well as a few A-capsids (empty). Virions (v) accumulate in invaginations of the inner nuclear membrane (INM) (i) which had formed multiple folds. ( B) A-, B- and C-capsids are scattered throughout the nucleus. Two C-capsids (bC) bud at the membrane of an invagination. Bars 500 nm.