Figure 8.

Cryo-field emission scanning electron microscopy (cryo-FESEM) images of the nuclear surface at 12 hpi with wt HSV-1 demonstrating in ( A) budding capsids (bo) under the outer nuclear membrane (ONM) (o) and at two sites where the ONM has been focally removed (b) during fracturing, as well as dilated nuclear pores (d) with or without protruding material. ( B) shows a virion (v) in the Perinuclear space (PNS), and a dilated nuclear pore (d) at the inner nuclear membrane (INM) (i) and at the ONM both occupied by protruding material. Bars 200 nm.