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. 2019 Jun 20;17:207. doi: 10.1186/s12967-019-1957-5

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Anti-tumor effect of PD-L1_241-265-specific CD4⁺ T-cell lines in vivo mouse model. a Scheme of adoptive transfer model. Tumor size was monitored in nude mice inoculated with b HLA-matched Lu65 (n = 6) and c HLA-unmatched Sa-3 (n = 6). Error bars indicate the SD of each mouse in the group. The graphs are representative of two separate experiments. Statistical analysis was performed in Prism using unpaired t test