Table 2.
The time-trend of dysphagia-free period with RBES in the model of HLM
| Fixed effects | Parameter (95% CI) | P | |
|---|---|---|---|
| Times | Intercept (d) | 72.7 (61.8–83.6) | <0.001 |
| Time-trend (d/time) | 12.7 (8.7–16.7) | <0.001 | |
| Patient characteristics | |||
| Sex | |||
| Female–reference category | Intercept (d) | 75.1 (54.3–95.9) | <0.001 |
| Time-trend (d/time) | 10.5 (2.3–18.7) | 0.014 | |
| Male | Intercept (d) | −3.2 (−27.8–21.4) | 0.802 |
| Time-trend (d/time) | 6.1 (−4.0–16.2) | 0.236 | |
| Age | |||
| Intercept (d) | 83.3 (46.4–120.2) | <0.001 | |
| Time-trend (d/time) | 23.6 (8.6–38.6) | <0.001 | |
| Intercept (d) | −0.17 (−0.8–0.4) | 0.557 | |
| Time-trend (d/time) | −0.17 (− 0.4–0.1) | 0.193 | |
| Stricture characteristics | |||
| Etiology | |||
| ESD/ESTD–reference category | Intercept (d) | 57.6 (35.6–79.6) | < 0.001 |
| Time-trend (d/time) | 14.7 (8.6–20.8) | 0.001 | |
| Achalasia of cardia | Intercept (d) | 154.2 (97.5–210.9) | < 0.001 |
| Time-trend (d/time) | −0.54 (−21.9–20.8) | 0.971 | |
| Surgery | Intercept (d) | 21.4 (−4.4–47.2) | 0.046 |
| Time-trend (d/time) | 9.01 (−6.7–24.7) | 0.154 | |
| Caustic | Intercept (d) | −1.19 (−21.0–18.6) | 0.931 |
| Time-trend (d/time) | −4.50 (−16.6–7.6) | 0.575 | |
| Location | |||
| Intercept (d) | 32.8 (7.1–58.5) | 0.015 | |
| Time-trend (d/time) | 5.53 (−4.3–15.3) | 0.273 | |
| Intercept (d) | 1.75 (0.7–2.8) | 0.002 | |
| Time-trend (d/time) | 0.36 (−0.1–0.8) | 0.101 | |
| Length | |||
| <2 cm-reference category | Intercept (d) | 87.7 (71.7–103.7) | <0.001 |
| Time-trend (d/time) | 17.6 (9.4–25.8) | <0.001 | |
| ≥2 cm | Intercept (d) | −26.8 (−48- -5.6) | 0.015 |
| Time-trend (d/time) | −6.32 (−16.1–3.5) | 0.212 | |
| Number | |||
| One-reference category | Intercept (d) | 79.9 (67.2–92.6) | <0.001 |
| Time-trend (d/time) | 14.9 (9.8–20.0) | <0.001 | |
| Two or more | Intercept (d) | −24.8 (−48- -1.6) | 0.040 |
| Time-trend (d/time) | −6.57 (−14.8–1.7) | 0.123 | |
| Therapy characteristics | |||
| Initial dysphagia-free period | |||
| Intercept (d) | 52.3 (36.3–68.3) | <0.001 | |
| Time-trend (d/time) | 17.6 (10.0–25.2) | <0.001 | |
| Intercept (d) | 0.46 (0.2–0.7) | 0.010 | |
| Time-trend (d/time) | −0.12 (−0.3–0.1) | 0.229 | |
| Therapy | |||
| Dilation + Stents–reference category | Intercept (d) | 74.9 (61.5–88.3) | <0.001 |
| Time-trend (d/time) | 17.4 (11.1–23.7) | <0.001 | |
| Stents | Intercept (d) | −6.6 (−30.1–16.9) | 0.583 |
| Time-trend (d/time) | −7.6 (−16.6–1.4) | 0.103 | |
RBES Refractory benign esophageal strictures
CI Confidence interval
HLM Hierarchical linear Model