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. 2019 Jun 20;20:367. doi: 10.1186/s13063-019-3468-3

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — SPIRIT figure providing an overview of time points, interventions, and assessments of the PACINPAT randomised controlled trial. BDNF brain-derived neurotrophic factor, 5-HTTLPR serotonin transporter polymorphic promoter region, IGF-1 insulin-like growth factor 1, PACINPAT Physical Activity Counselling in IN-PATients, SPIRIT Standard Protocol Items: Recommendations for Interventional Trials, TNF-α tumor necrosis factor alpha