Figure 4.
Inhibitory effect of ketoconazole and levofloxacin each alone and in combination (using different concentrations of levofloxacin) on biofilm formation by the tested Staphylococcus aureus strains. (A) Effect of ketoconazole, ¼×MIC of levofloxacin each alone and in combination. (B) Effect of ketoconazole, ½×MIC levofloxacin each alone and in combination. (C) Effect of ketoconazole, 1×MIC levofloxacin each alone and in combination. (D) Effect of ketoconazole, 2×MIC levofloxacin each alone and in combination. Data represent the mean±SD of two different experiments performed in triplicate. **Highly significant, P<0.001 (Student’s t-test).
Abbreviations: LEV, levofloxacin; MIC, minimum inhibitory concentration.