Figure 2.
Effect of Lactobacillus fermentum UCO-979C and L. fermentum CRL973 on the expression of factors from the complement and coagulation systems in porcine intestinal epithelial (PIE) cells. PIE cells were pre-treated with UCO-979C or CRL973 strains for 48 h and then stimulated with heat-stable Enterotoxigenic Escherichia coli (ETEC) pathogen-associated molecular patterns (PAMPs). The expression of factors from the complement (C1S, C1R, C3, and CFB) and coagulation (F3) systems were studied at 48 h after lactobacilli stimulation (basal) or at 12 h after heat-stable ETEC PAMPs challenge. The results represent three independent experiments. Results are expressed as mean ± SD. Significantly different from control PIE cells at the same time point *(P < 0.05), **(P < 0.01).