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. 2019 Jun 3;28(11):717–733. doi: 10.1089/scd.2018.0194

FIG. 11.

FIG. 11.

8-OHdG expression (arrows) in liver and cartilage buds of embryos derived from dams previously treated with 5azaC and/or PBN, detected by immunohistochemistry: (A) cartilage, control; (B) cartilage, 5azaC; (C) liver, control; (D) liver, 5azaC. DAB, hematoxylin counterstain. Thick arrows point to internal negative control signal. H-score in cartilage (E) and liver (F). Boxplot shows apoptotic index distribution (box denotes median, and whiskers denote the smallest and the largest observation). ANOVA, Holm–Sidak's multiple-comparison post hoc test. ***P < 0.0001. Color images are available online.