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. 2019 May 28;78(7):996–1002. doi: 10.1136/annrheumdis-2019-215046

Table 1.

Number of patients with myositis with myositis-specific or associated autoantibodies

Antibody Adult-onset IIM Juvenile-onset IIM Total number positive
(Adult+juvenile-onset)
Number tested Number antibody positive Number tested Number antibody positive
Jo-1 1937 325 (16.8%) 447 7 (1.6%) 332
TIF1 1697 91 (5.4%) 356 106 (29.8%) 197
PM/Scl 1883 120 (6.4%) 457 16 (3.5%) 136
Mi-2 1884 87 (4.6%) 456 17 (3.7%) 104
NXP2 1502 28 (1.9%) 360 65 (18.1%) 93
cN1A 232 46 (19.8%) 81 18 (22.2%) 64
SRP 1822 45 (2.5%) 457 0 45
HMGCR 1264 51 (4.0%) 130 1 (0.8%) 52
MDA5 1674 18 (1.1%) 402 17 (4.2%) 35
SAE 1518 31 (2.0%) 397 0 31
PL7 1927 23 (1.2%) 457 0 23
PL12 1927 11 (0.6%) 457 0 11

Myositis-specific/associated autoantibodies n>10 in cohort, stratified by adult-onset and juvenile-onset disease. Frequency is of those patients tested for each autoantibody within the cohort, where testing was not necessarily random.

IIM, idiopathic inflammatory myopathies.