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. 2019 Mar 12;74(7):643–649. doi: 10.1136/thoraxjnl-2018-212638

Table 1.

Characteristics of the training cohort

(A) Training Lung cancer
(n=50)
Benign nodules
(n=42)
P value*
Male, n (%) 25 (50) 28 (67) 0.162
Age (years), mean (SD) 63.6 (7.1) 65.2 (6.9) 0.261
Current smoker, n (%) 32 (64) 19 (45) 0.111
Pack-years, mean (SD) 60.35 (24.11) 61.81 (22.81) 0.766
Years since quit smoking, mean (SD) 1.52 (2.88) 3.25 (3.95) 0.020
Nodule size in diameter (mm), mean (SD) 13.43 (6.14) 9.74 (6.69) 0.007
Nodule number, n (%)† 0.203
 Solid 28 (56) 34 (81)
 Non-solid/mixed 22 (44) 8 (19)
Vessel number, mean (SD) 9.22 (9.48) 2.26 (2.21) <0.001
(B) Validation Lung cancer
(n=44)
Benign nodules
(n=82)
P value*
Male, n (%) 23 (52) 48 (59) 0.626
Age, mean, years (SD) 65.23 (9.62) 66.93 (7.54) 0.313
Current smoker, n (%) 37 (84) 36 (44) <0.001
Pack-years, mean (SD)‡ 49.41 (22.79) 49.49 (22.0) 0.985
Years since quit smoking, mean (SD) 0.477 (1.50) 3.037 (4.33) <0.001
Nodule size in diameter (mm), mean (SD) 18.86 (7.12) 11.57 (5.76) <0.001
Nodule number, n (%)† 0.981
 Solid 28 (78) 54 (68)
 Non-solid/mixed 8 (22) 25 (32)
Vessel number, mean (SD) 18.57 (5.21) 3.02 (3.98) <0.001

*Two-sided p values were based on t-test and χ2 test for continuous and categorical variables, respectively.

†Nodule type was unmeasured for 11 subjects (8 with cancer).

‡Pack-years was unmeasured for 5 subjects (4 with cancer).