Table 3.
Impact of Different Time Intervals on 90‐Day Good Outcome (mRS 0‐2) With Successful Reperfusion (mTICI 2b‐3) After Thrombectomy According to Baseline DWI pc‐ASPECTS
| DWI pc‐ASPECTS <8 (n=33) | DWI pc‐ASPECTS ≥8 (n=28) | P Value for Heterogeneity | |
|---|---|---|---|
| Good outcome (90‐day mRS≤2), n (%) | 13 (39.4) | 15 (53.6) | … |
| Symptoms to reperfusion, min | 374 (265‐505)a | 371 (311‐461)a | … |
| Unadjusted OR (95% CI) | 0.90 (0.79‐1.03) | 0.99 (0.88‐1.11) | 0.28 |
| Adjusted OR (95% CI)b | 0.87 (0.73‐1.02) | 0.93 (0.81‐1.06) | 0.46 |
| Symptoms to imaging, min | 121 (102‐224)a | 145 (107‐190)a | … |
| Unadjusted OR (95% CI) | 0.99 (0.88‐1.11) | 0.96 (0.84‐1.10) | 0.72 |
| Adjusted OR (95% CI)b | 0.99 (0.82‐1.19) | 0.88 (0.74‐1.03) | 0.34 |
| Imaging to groin puncture, min | 140 (107‐176) | 157 (121‐210) | … |
| Unadjusted OR (95% CI) | 0.66 (0.42‐1.04) | 1.19 (0.86‐1.64) | 0.037 |
| Adjusted OR (95% CI)b | 0.48 (0.21‐1.07) | 1.23 (0.83‐1.80) | 0.045 |
| Imaging to reperfusion, min | 194 (169‐291)a | 237 (167‐283)a | … |
| Unadjusted OR (95% CI) | 0.61 (0.39‐0.94) | 1.06 (0.80‐1.41) | 0.032 |
| Adjusted OR (95% CI)b | 0.40 (0.18‐0.85) | 1.10 (0.79‐1.51) | 0.020 |
Odds ratios were calculated per 30‐min increase. DWI pc‐ASPECTS indicates diffusion‐weighted imaging posterior‐circulation Alberta Stroke Program Early Computed Tomography Score; IQR, interquartile range; mRS, modified Rankin Scale; mTICI, modified Treatment In Cerebral Infarction; OR, odds ratio.
a
Median (IQR).
b
Adjusted for the following prespecified confounders: reperfusion grade (mTICI 2b vs 3), age, and admission NIHSS.