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. 2019 May 25;8(11):e012421. doi: 10.1161/JAHA.119.012421

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© 2019 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Patient‐reported outcomes by latent profile group (n=496). Latent profile analysis identified 5 subgroups based on PROMIS/NeuroQoL domains of pain, depression, cognitive function, fatigue, social role satisfaction, function, and modified Rankin Scale score. Depression was measured with the Patient Health Questionnaire 9 depression screen, which was cocalibrated on the PROMIS metric to provide an equivalent PROMIS depression score. PROMIS and NeuroQoL scores are oriented so that higher scores indicated worse symptoms or function. Mean score of the US general population is 50. hrQoL indicates health‐related quality of life; NeuroQoL, Quality of Life in Neurological Disorders; PROMIS, Patient‐Reported Outcome Measurement Information System.