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. 2019 May 25;8(11):e011260. doi: 10.1161/JAHA.118.011260

Figure 2.

Figure 2

O‐linked β‐N‐acetylglucosamine (O‐GlcNAc) transferase (OGT) and O‐GlcNAc protein levels in early hypertrophy. Immunoblot results are shown for OGT (A), total protein O‐GlcNAc levels (B), and O‐GlcNAc levels at the indicated specific molecular weight ranges (C). Values are arbitrary units reported as mean±standard error of the mean. n=3 control sham, n=3 OGT knockout (OGTKO) sham, n=4 control transverse aortic constriction (TAC), n=4 OGTKO TAC. In (A and B) *P<0.05 between groups indicated with the bar. In (C) *P<0.05 for control sham vs control TAC in same molecular weight range; ‡ P<0.05 for control sham vs OGTKO sham in the same molecular weight range; § P<0.05 for control TAC vs OGTKO TAC at the same molecular weight range; † P<0.05 for OGTKO sham vs OGTKO TAC at the same molecular weight range. For (B) control sham vs OGTKO sham, P value from t test=0.039 and P value from Tukey procedure=0.14. For (C) >150 kDa OGTKO sham vs OGTKO TAC, P value from t test=0.023 and P value from Tukey procedure=0.12. For (C) 150 to 75 kDa control sham vs OGTKO sham, P value from t test=0.022 and P value from Tukey procedure=0.25.