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. 2019 May 25;8(11):e011260. doi: 10.1161/JAHA.118.011260

Figure 3.

Figure 3

O‐linked β‐N‐acetylglucosamine (O‐GlcNAc) transferase (OGT) and O‐GlcNAc protein levels in established hypertrophy. Immunoblot results are shown for OGT (A), total protein O‐GlcNAc levels (B), O‐GlcNAc levels at the indicated specific molecular weight ranges (C), and O‐GlcNAc protein levels at molecular weights <100 kDa in control (cont) sham and control transverse aortic constriction (TAC) (D). Values are arbitrary units reported as mean±standard error of the mean. For (A through C) n=3 control sham, n=3 O‐GlcNAc transferase knockout (OGTKO) sham, n=4 control TAC, n=4 OGTKO TAC. For D, n=7 control sham and n=7 control TAC. In (A, B, and D) *P<0.05 between groups indicated with the bar. In (C) ‡ P<0.05 for control sham vs OGTKO sham at the same molecular weight range; § P<0.05 for control TAC vs OGTKO TAC at the same molecular weight range; † P<0.05 for OGTKO sham vs OGTKO TAC at the same molecular weight range. For (C) >150 kDa control sham vs OGTKO sham, P value from t test=0.072 and P value from Tukey procedure=0.027. For (C) >150 kDa OGTKO sham vs OGTKO TAC, P value from t test=0.025 and P value from Tukey procedure=0.25.