Table 4.

Echocardiogram Measurements Immediately Before and on Day 7 of Tam Injections in a Cohort of OGTKO Mice With Early Hypertrophy

	Pre‐Tam (n=7)	Day 7 Tam (n=7)
HR, bpm	455±14	455±17
EDD, mm	4.5±0.1	4.5±0.1
ESD, mm	3.5±0.0	3.5±0.1
LVPWd, mm	0.71±0.02	0.74±0.02
FS, %	20.8±1.0	21.9±1.2
EF, %	42.3±1.7	44.3±2.0

Values are expressed as mean±standard error of the mean. A separate cohort of early hypertrophy O‐linked β‐N‐acetylglucosamine transferase knockout (OGTKO) mice had echocardiograms performed immediately before starting 4‐hydroxytamoxifen (Tam) injections (Pre‐Tam) and on day 7 of Tam injections (Day 7 Tam). P>0.05 by paired t test for all measurements. bpm indicates beats per minute; EDD, left ventricular end‐diastolic diameter; EF, left ventricular ejection fraction; ESD, left ventricular end‐systolic diameter; FS, left ventricular fractional shortening; HR, heart rate; LVPWd, left ventricular posterior wall thickness in diastole.