Table 2.
Baseline Laboratory and Echocardiography Studies of DC and VC
| Characteristic | DC (n=903) | VC (n=185) | P Value |
|---|---|---|---|
| Laboratory studies: median (interquartile range) | |||
| White blood cell count, cells ×103/mm3 | 13.5 (10.5–17.3) | 13.3 (10.1–16.6) | 0.406 |
| Neutrophils, % | 59 (47–71) | 61 (41–71) | 0.328 |
| Hemoglobin, g/dL | 11.1 (10.4–11.8) | 10.9 (10.1–11.7) | 0.047 |
| Hematocrit, % | 32.4 (30.7–34.5) | 32.0 (30.0–34.0) | 0.066 |
| Platelets, cells ×103/mm3 | 366 (287–457) | 389 (303–464) | 0.190 |
| CRP, mg/dL | 7.9 (4.5–15.2) | 7.2 (4.0–15.3) | 0.295 |
| Sodium–mmol/L | 135 (133–137) | NA | |
| AST, U/L | 36 (26–55) | NA | |
| ALT, U/L | 38 (19–103) | 32 (16–84) | 0.062 |
| Albumin, g/dL | 3.6 (3.2–4.0) | 3.3 (2.8–3.7) | <0.001 |
| Total bilirubin, mg/dL | 0.3 (0.2–0.7) | NA | |
| Baseline echocardiography, mean±SD | |||
| RCA Z score | 0.94±1.37 | 1.21±1.39 | 0.019 |
| LAD artery Z score | 1.18±1.66 | 1.13±1.55 | 0.665 |
| Maximum Z score of the LAD artery and RCA | 1.61±1.59 | 1.69±1.50 | 0.503 |
| RCA Z score | |||
| ≥2.00 | 148 (16) | 36 (20) | 0.277 |
| ≥2.50 | 88 (10) | 26 (14) | 0.083 |
| ≥3.00 | 57 (6) | 15 (8) | 0.327 |
| LAD artery Z score | |||
| ≥2.00 | 195 (22) | 40 (22) | 1.000 |
| ≥2.50 | 122 (14) | 29 (16) | 0.415 |
| ≥3.00 | 76 (8) | 17 (9) | 0.772 |
| Maximum baseline Z score | |||
| ≥2.00 | 264 (29) | 55 (30) | 0.929 |
| ≥2.50 | 170 (19) | 42 (23) | 0.223 |
| ≥3.00 | 110 (12) | 27 (15) | 0.394 |
| Baseline CAAs | |||
| Small CAAs (Z score ≥2.5–5) | 149 (16) | 38 (21) | 0.394 |
| Medium CAAs (Z score ≥5 to ≤10) | 15 (2) | 4 (2) | |
| Large or giant CAAs (Z score ≥10 or absolute dimension ≥8 mm) | 6 (1) | 0 (0) | |
ALT indicates alanine aminotransferase; AST, aspartate aminotransferase; CAAs, coronary artery aneurysms; CRP, C‐reactive protein; DC, development cohort; LAD, left anterior descending; NA, not available; RCA, right coronary artery; VC, validation cohort.