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. 2019 May 30;8(11):e010814. doi: 10.1161/JAHA.118.010814

Table 5.

Clinical Features Associated With 1‐Month Disability

Variables Good mRS, (n=−626), % Poor mRS (n=394), % Unadjusted Risk Estimates Adjusted Risk Estimates
RR 95% CI P Value RR 95% CI P Value
Age (mean), y 57.7 (13.9) 62.4 (14.4) 1.01 1.01–1.02 <0.0001 ··· ··· ···
Age >60 y 45.1 59.4 1.43 1.18–7.73 <0.0001 1.42 1.06–1.88 0.017a
Sex
Male 61.7 52.5
Female 38.3 47.5 1.26 1.05– 1.51 0.015a 1.05 0.80–1.39 0.720
Education
No formal education 12.6 16.4 1.00 ··· ··· 1.00 ··· ···
Primary 15.3 24.7 1.12 0.85–1.47 0.420 0.91 0.62–1.33 0.622
Secondary 30.8 23.6 0.72 0.54–0.97 0.030a 0.65 0.42–0.99 0.046a
Higher 41.3 35.3 0.78 059–1.02 0.068 0.77 0.53–1.11 0.163
Hypertension 73 79.7 1.27 1.00–1.62 0.047a 1.22 0.87–1.71 0.246
Diabetes mellitus 14.3 9.8 0.76 055–1.06 0.107 ··· ··· ···
Dyslipidemia 62.5 67 1.13 0.93–1.38 0.216 ··· ··· ···
BMI 26.8 (5.19) 26.5 (5.41) 0.99 0.97–1.01 0.425 ··· ··· ···
Echo parameters
Left atrial diameter 3.07 (2.68) 3.01 (1.26) 0.99 0.95–1.04 0.808 ··· ··· ···
Aortic root diameter 3.05 (0.76) 3.00 (0.54) 0.93 0.79–1.10 0.403 ··· ··· ···
Aortic valvular opening, cm 1.99 (0.99) 1.90 (0.47) 0.85 0.65–1.12 0.261 ··· ··· ···
LVID 4.44 (0.95) 4.32 (1.06) 0.91 0.82–1.01 0.082 0.99 0.75–1.31 0.977
LVIDs 3.18 (1.78) 3.35 (4.65) 1.02 1.01–1.02 <0.0001 0.97 0.75–1.24 0.789
IVSTD 1.45 (0.98) 1.43 (0.58) 0.98 0.86–1.13 0.828 ··· ··· ···
IVSTS 1.66 (0.57) 1.69 (0.56) 1.06 0.88–1.26 0.549 ··· ··· ···
LVPWTD 1.43 (0.81) 1.53 (0.76) 1.07 0.97–1.18 00.189 ··· ··· ···
LVPWTS 1.88 (1.04) 2.17 (1.62) 1.08 1.07–1.069 0.010a 1.11 1.07–1.15 <0.001a
EF, % 63.0 (27.3) 61.9 (34.7) 0.99 0.99–1.00 1.00 ··· ··· ···
EF <50% 16.9 20.4 1.15 0.91–1.44 0.248 ··· ··· ···
FS, % 34.0 (11.4) 36.2 (28.6) 1.00 0.98–1.01 0.989 ··· ··· ···
LVM indexed by height 244.5 (107.8) 237.9 (108.2) 0.99 0.99–1.01 0.800 ··· ··· ···
Abnormal LVM 63.6 63.0 0.98 0.72–1.34 0.915 ··· ··· ···
LV geometry
Normal 14 7.7 1.00 ··· ··· 1.00 ··· ···
Concentric remodeling 23.5 26.8 1.66 0.98–2.82 0.062 1.35 0.74–2.47 0.325
Concentric hypertrophy 7.3 9.5 1.80 0.97–5.73 0.058 1.77 0.89–3.52 0.103
Eccentric hypertrophy 55.2 56 1.54 0.94–3.56 0.095 1.48 0.86–2.55 0.158
LV systolic dysfunction
None 72.8 69.1 1.00 ··· ··· ··· ··· ···
Mild 18.6 20.7 1.17 0.92–1.48 0.207 ··· ··· ···
Moderate 5.7 6 1.11 0.81–1.52 0.529 ··· ··· ···
Severe 3 4.2 1.30 0.80–2.12 0.292 ··· ··· ···

BMI indicates body mass index; EF, ejection fraction; FS, fractional shortening; IVSTD, interventricular septal thickness at end diastole; IVSTS, interventricular septal thickness at end systole; LV, left ventricular; LVID, left internal dimension at diastole; LVIDs, left internal dimension at systole; LVM, left ventricular mass; LVPWTD, left ventricular posterior wall thickness at diastole; LVPWTS, left ventricular posterior wall thickness at systole; mRS, modified Rankin Scale; RR, relative risk.

a

P<0.05.