Table 3.
Drink A | Drink B | Placebo | P Valuea | |
---|---|---|---|---|
ECG parametersb | ||||
QTcB, ms | 17.9 (13.9)c | 19.6 (15.8)d | 11.9 (11.1) | 0.005 |
QTcF, ms | 15.0 (11.8)c | 15.2 (11.9)d | 6.9 (7.1) | <0.001 |
QT, ms | 18.4 (17.0)c | 15.8 (13.3) | 10.2 (12.2) | 0.026 |
PR, ms | 5.4 (6.5) | 6.1 (7.5) | 8.6 (6.6) | 0.076 |
QRSd, ms | 6.2 (3.3) | 5.9 (3.0) | 5.0 (2.9) | 0.164 |
HR, bpm | 7.7 (7.4) | 7.2 (6.8) | 7.4 (5.9) | 0.918 |
Hemodynamicsb | ||||
SBP, mm Hg | 15.9 (5.0)c | 14.4 (4.8)d | 9.8 (4.8) | <0.001 |
DBP, mm Hg | 9.6 (4.1)c | 9.6 (4.9)d | 6.1 (3.8) | <0.001 |
cSBP, mm Hg | 11.1 (4.7)c | 10.1 (4.8)d | 6.5 (3.5) | <0.001 |
cDBP, mm Hg | 9.9 (4.2)c | 9.8 (5.1)d | 6.7 (3.5) | <0.001 |
All data reported as mean (SD). cDBP indicates central diastolic blood pressure; cSBP, central systolic blood pressure; DBP, diastolic blood pressure; HR, heart rate; PR, PR interval; QRSd, QRS duration; QT, QT interval; QTcB, Bazett's corrected QT interval; QTcF, Fridericia's corrected QT interval; SBP, systolic blood pressure.
P value for analysis of variance adjusted for subject variability.
No statistically significant difference was noted between drink A and drink B for any parameter.
Statistically significant difference between drink A and placebo.
Statistically significant difference between drink B and placebo.