Table 1.
Demographics of Hypertensive Patients and HVs Included in the Study
| Parameter | HV | EH | RVH |
|---|---|---|---|
| Demographics | |||
| No. of patients | 14 | 14 | 14 |
| Age, y | 72.3 (64–79) | 69.9 (64–78) | 70 (58–79) |
| Sex (female/male) | 8/6 | 7/7 | 9/5 |
| BMI, kg/m2 | 25.3±3.4 | 27.3±4.3 | 29.1±3.95 |
| Renal function | |||
| Creatinine, mg/dL | 0.95 (0.7–1.2) | 1.0 (0.5–1.5) | 1.2 (0.7–1.9) |
| eGFR, mL/min/1.73 m2 | 80.5±10.4 | 72.4±18.2 | 62.8±21.6b |
| Related laboratory measures | |||
| Urine protein, mg/mLa | 96.1 (4–290) | 67 (29–213) | 86.4 (26–255) |
| Mean blood pressure, mm Hg | 87.8±7.9 | 91.3±13.1 | 92.1±9.4 |
| Systolic blood pressure, mm Hg | 120.4±9.3 | 136.6±18.2b | 135.6±20.4b |
| Diastolic blood pressure, mm Hg | 71.4±8.6 | 68.6±13.9 | 70.4±8.1 |
| Total cholesterol, mg/dL | 175.4±30.5 | 178.4±33.7 | 174.8±38.4 |
| Triglycerides, mg/dL | 116.1 (51–207) | 128.9 (85–201) | 127.1 (73–249) |
| HDL, mg/dL | 60.1 (42–88) | 48.7 (35–79) | 52.2 (34–79) |
| LDL, mg/dL | 97.2±28.9 | 103.9±25.2 | 97.1±30.9 |
| Renal oxygenation | |||
| RFH (%R2* >30 1/s) | 9 (1.20–26.25) | 20.5 (4.60–36.05)c | |
| Renal cortical R2* (1/s) | 18.2 (16.45–20.35) | 21.5 (17.3–30.4)c | |
BMI indicates body mass index; eGFR, estimated glomerular filtration rate; EH, essential hypertension; HDL, high‐density lipoprotein; HVs, healthy volunteers; LDL, low‐density lipoprotein; RBF, renal blood flow; RFH, renal fractional hypoxia; RVH, renovascular hypertension.
a
Spot urine samples were collected in HVs and 24 hours in EH and RVH.
b
P<0.05 vs HVs.
c
P<0.05 vs EH.