Fig. 2.
Role of DC subsets in responses to poly-ICLC and pam-peptide crosspresentation. a, b WT or BATF3-KO mice were vaccinated with pam-Trp1 (pam2-KMVFTAPDNLGYM) + poly-ICLC and the Trp1-specific CTL percentages in blood (a) and total numbers in spleens (b) were evaluated. c WT or BATF3-KO mice received 105 naïve OT-I cells followed by one dose of pam-Ova + poly-ICLC and 7 days later the absolute numbers of OT-I cells were evaluated in spleens. d–f WT or BATF3-KO mice were injected with poly-ICLC (50 µg, i.v.) and 18 h later the serum levels of IFN-I, IL15/IL15Rα complexes, and IL12p40 were measured. Results are presented as individual mice (each symbol) with the mean ± SD for each group