Table S3.
Health-utility values and health-related quality-of-life scores by history of long hospital stays and frequency of visits to medical professionals due to hemophilia in subsample of subjects with severe hemophilia (n=130)
| History of long hospital stays | Frequency of visits to medical professionals due to hemophilia | ||||||
|---|---|---|---|---|---|---|---|
| Yes (n=73) | No (n=57) | >Once a month (n=2) | Every 1–3 months (n=24) | Every 4–6 months (n=32) | Every 6–12 months (n=56) | <Once every 12 months (n=16) | |
|
EQ-5D-3L index score Mean (SD) Median Range |
0.57 (0.32) 0.66 –0.48–1 |
0.75 (0.23) 0.74 –0.02–1 |
0.44 (0.50) 0.44 0.08–0.80 |
0.55 (0.31) 0.59 –0.02–1 |
0.64 (0.34) 0.69 –0.48–1 |
0.71 (0.26) 0.71 –0.02–1 |
0.66 (0.30) 0.67 –0.02–1 |
| P-value | <0.001 | 0.248 | |||||
|
EQ-5D-5L index score Mean (SD) Median Range |
0.66 (0.26) 0.73 0.04–1 |
0.79 (0.23) 0.88 0.07–1 |
0.60 (0.39) 0.60 0.33–0.88 |
0.68 (0.25) 0.77 0.08–1 |
0.71 (0.30) 0.83 0.04–1 |
0.75 (0.23) 0.79 0.07–1 |
0.71 (0.22) 0.73 0.19–1 |
| P-value | 0.005 | 0.750 | |||||
|
SF-6D score Mean (SD) Median Range |
0.66 (0.12) 0.64 0.39–0.95 |
0.72 (0.12) 0.72 0.52–1 |
0.61 (0.25) 0.61 0.43–0.79 |
0.63 (0.09) 0.61 0.52–0.85 |
0.69 (0.14) 0.72 0.39–0.89 |
0.71 (0.12) 0.68 0.49–1 |
0.70 (0.13) 0.66 0.50–0.94 |
| P-value | 0.006 | 0.105 | |||||
|
SF-36 PCS Mean (SD) Median Range |
36.3 (12.7) 32.8 16.3–63.8 |
42.9 (11.6) 41.0 19.8–61.6 |
37.0 (5.7) 37.0 33.0–41.0 |
36.5 (10.1) 34.1 24.3–56.7 |
38.3 (15.3) 37.6 16.3–63.8 |
41.1 (12.2) 40.5 19.8–59.8 |
38.5 (12.4) 37.6 21.2–61.1 |
| P-value | 0.003 | 0.627 | |||||
|
SF-36 MCS Mean (SD) Median Range |
46.3 (11.6) 48.0 24.9–70.1 |
49.1 (10.5) 50.9 22.6–65.4 |
45.7 (27.0) 45.7 26.6–64.7 |
44.3 (9.0) 45.4 24.9–56.6 |
47.6 (11.8) 49.6 26.4–70.1 |
48.7 (11.0) 50.2 22.6–65.4 |
48.6 (12.0) 49.9 28.3–68.7 |
| P-value | 0.147 | 0.593 | |||||
Abbreviations: EQ-5D-3L, EuroQol — five dimensions, three levels; SF, Short-Form Health Survey; PCS, physical component summary; MCS, mental CS.