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. Author manuscript; available in PMC: 2020 Apr 1.
Published in final edited form as: J Mol Cell Cardiol. 2019 Feb 13;129:92–104. doi: 10.1016/j.yjmcc.2019.01.015

Figure 3. MRTFepiDKO mice are protected from pathological fibrotic remodeling following MI.

Figure 3

(A) Representative WT and MRTFepiDKO heart sections stained with TTC and quantitated in (B) 24 hours post-MI. 111 cytokines were measured and categorized as unchanged (black), upregulated (green) or downregulated (red). Screen was performed in (C) Non-injured mice and (D) Mice subjected to MI for 3-days. (E) List of downregulated cytokines in MRTFepiDKO serum relative to WT serum at baseline and 3-days post-MI. Representative dot blot images of (F) Periostin and IL-1α / IL-1F1 at 3-days post MI.

Scale bar (A) = 1mm.