Table 2.
Effect of Echinacea purpurea root (100 and 200 mg/kg) on some hematological parameters in different groups
| Parameters | Experimental groups | |||
|---|---|---|---|---|
| Group I (control) | Group II (CsA) | Group III (CsA + EPR) (100 mg/kg BW) | Group IV (CsA + EPR) (200 mg/kg BW) | |
| Hb (g/dl) | 14.97±0.77 | 9.85±0.82a,*** | 13.83±0.48b,*** | 14.29±0.56b,*** |
| RBCs (×1012/L) | 8.80±0.26 | 7.86±0.20a,* | 8.40±0.22 | 8.24±0.17 |
| MCH (pg) | 18.28±0.54 | 14.07±0.39a,*** | 17.57±0.49b,*** | 18.58±0.44b,*** |
| WBCs (×109/L) | 6.17±0.53 | 1.94±0.14a,*** | 6.89±0.51b,*** | 6.33±0.65b,*** |
| Lymphocytes (×109/L) | 2.30±0.17 | 1.76±0.08a,* | 2.08±0.1 | 2.40±0.17b,** |
Data are mean±SE (n=8). aSignificant difference from control, bSignificant difference from CsA, cSignificant difference between CsA + EPR (100 mg/kg BW) and CsA + EPR (200 mg/kg BW), *P<0.05, **P<0.01 and ***P<0.001(. SE: Standard error, BW: Body weight, EPR: Echinacea purpurea root, CsA: Cyclosporine, Hb: Hemoglobin, RBCs: Red blood cell count, MCH: Mean corpuscular hemoglobin, WBCs: White blood cell count