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. 2019 Jun 27;92(2):327–335.

Figure 2.

Figure 2

Current working model of the hierarchical multi-oscillatory mammalian circadian system. Light (via the eye) entrains the SCN and non-photic inputs (e.g. food, palatable meal, wheel-running) entrain (via unknown pathways) extra-SCN pacemakers. The SCN and extra-SCN pacemakers coordinate the phases of peripheral oscillators. The output pathways that control overt rhythms of behavior and physiology are largely unknown. Dotted lines represent unknown pathways.